Los Angeles Clippers Vs. Los Angeles Lakers, NBA Betting Picks, Parlays and Predictions for Novemeber 25th, 2025 

King James Returns to Kick Clippers While They're Down

The LA Clippers and the Los Angeles Lakers renew their hallway rivalry tonight (well, sort of, now that the Clippers have their own digs), but the vibe is heavily tilted toward the Purple and Gold. The Lakers are absolutely rolling right now, riding a wave of momentum that has them looking like legitimate contenders rather than just play-in hopefuls. The offense is clicking, the rotations are crisp, and there's a real sense of purpose in how they’re moving the rock.

The headline, obviously, is the return of the King. LeBron James is back in the lineup after a brief stint on the sidelines, and his return couldn't come at a worse time for a Clippers squad that has been struggling to find its footing.

The Clippers have looked disjointed defensively, often getting caught in rotation and giving up way too many open looks from deep. You can't do that against this Lakers team, especially with LeBron orchestrating the attack and AD dominating the paint. The Clips are going to need a monster night from James Harden to keep this competitive, but "The Beard" has been hot and cold, and if he’s not hitting step-backs early, this game could get ugly fast. 

The Lakers have the depth, the star power, and frankly, the swagger right now. They know they’re the big dogs in town, and tonight is just another chance to remind their neighbors who runs LA.

Betting Picks & Predictions

Vegas sees a mismatch here, pegging the Lakers as 6 1/2-point favorites with a total set at 229. That spread feels about right given the Lakers' current form, but the total is the interesting number. The Over is 3-4 for the Lakers as favorites this season, meaning their games have trended slightly defensive or blowout-heavy when they are expected to win. 

However, with LeBron back pushing the pace and the Clippers' defense being porous lately, we might see a shootout. The Lakers are on a tear, and the Clippers just don't have the defensive chops to slow them down tonight. Prediction: Lakers win and cover, 120-110 (Over 229).